A comparative study on different market samples and standard samples of Shalaparni through physicochemical methods and near infrared spectroscopy.

Dashmoolais one of the most important groups explained in Mishrakagana. One of which, Shalaparni is a potent drug used single as well as in various formulations mentioned in classics. Adulteration in Dashmoolaplants is a very big issue now days and this is because of the lack of availability of the original drugs. In this study market samples of Shalaparni (Desmodium gangeticum DC.) collected from the different part of India; compared with the standard Shalaparni authenticated sample which was collected from the natural source; by using physicochemical parameter and near infrared spectroscopy. Results were statistically processed by PCA. The results show that there is no similarity found outbetween the standard drug and market samples of Shalaparni which were collected from different regions of India. The market samples were observed for different adulterated material having poor quality.

Anti‑inflammatory activity of root bark and stem bark of Shyonaka.

Background: Shyonaka (Oroxylum indicum Vent.; Bignoniaceae) root bark is one of the ingredients of dashamoola (a group of 10 roots), and is used for its anti‑inflammatory and analgesic action in a number of compound formulations in Ayurveda. Aim: Ayurvedic Pharmacopoeia of India (API) recommends using the stem bark instead of root bark. Material and Methods: An attempt has been made to study the anti‑inflammatory activity of both root bark and stem bark kashaya (decoction) experimentally. Conclusion: Results showed significant anti-inflammatory activity of root bark and stem bark decoction.

A comparative study of subsyde-CR versus meloxicam in rheumatic disorders.

A prospective, randomised comparative clinical study was conducted in adult patients of either sex presenting with articular and non-articular rheumatic conditions commonly encountered in clinical practice Rheumatoid arthritis, osteo-arthritis, cervical spondylosis, and lumbago/sciatica were the most frequent conditions encountered in both the groups, followed by others like tenosynovitis, frozen shoulder, prolapsed disc, fibrositis, myositis, sprains, strains and so on. The drugs that were employed for therapy were diclofenac in a controlled release formulation employing the DRCM technology (subsyde-CR) and meloxicam in a standard formulation marketed in our country. Both drugs were well tolerated and found to be effective in reducing the signs and symptoms of the disease entities throughout the study period, but subsyde-CR was observed to produce a somewhat greater reduction in signs and symptoms scores that meloxicam, a difference that could be possibly attributed to the greater efficacy of subsyde-CR in non-articular rheumatic conditions. On the basis of the available literature on diclofenac and meloxicam as well as the DRCM technology in formulating subsyde-CR, it is reasonable to conclude that a controlled release formulation of diclofenac based on the DRCM technology offers a safe and effective alternative to other non-steroidal anti-inflammatory drugs such as meloxicam.

Two stage reconstruction for the Shepherd's crook deformity in a case of polyostotic fibrous dysplasia.

Polyostotic fibrous dysplasia leads to progressive and disabling deformity involving the proximal femur. Conventional methods of treatment have been ineffective in controlling this problem. Two stage reconstruction was carried out in a case of polyostotic fibrous dysplasia with bilateral shepherd's crook deformity. Bilateral subtrochanteric osteotomies with intramedullary fixation in the first stage and intertrochanteric osteotomies in the second stage with nail plate fixation was done to provide definitive control of the deformity. Bone graft was not used.

Is McMurray's osteotomy obsolete?

A review of the method of performing, advantages, disadvantages of McMurray's displacement osteotomy with regard to treatment of nonunion of transcervical fracture neck femur with viable femoral head was carried out in this study of ten cases, in view of the abandonment of the procedure in favour of angulation osteotomy. Good results obtained in the series attest to the usefulness of McMurray's osteotomy in the difficult problem of nonunion of transcervical fracture neck femur in well selected cases with certain advantages over the angulation osteotomy due to the 'Armchair effect'.

Bizarre parosteal osteochondroma in the foot (a case report).

A rare case of a bizarre parosteal osteochondroma in the foot is presented. The tumour first described in 1983 by Nore et al is rare in any location and has to be differentiated from a juxta-cortical osteosarcoma and a benign osteosarcoma. Its differentiating characteristics are discussed.